Atypical Thymic Carcinoid in a Patient with Zollinger-Ellison Syndrome
نویسندگان
چکیده
منابع مشابه
Metastatic gastrinoma in a pediatric patient with Zollinger-Ellison syndrome.
Metastatic neuroendocrine tumors of childhood are extremely rare, and as such present diagnostic and therapeutic challenges. Here, we report a case of gastrinoma with extensive hepatic metastases in a pediatric patient with Zollinger-Ellison Syndrome who underwent orthotopic liver transplant followed by cytotoxic chemotherapy, somatostatin analog therapy, and immune modulation.
متن کاملZollinger-Ellison syndrome
Since Zollinger and Ellison described in 1955 a pathological entity consisting of multiple recurrent peptic ulcerations, gastric hypersecretion, and islet cell tumours of the pancreas, several reports have been published dealing with the clinical and biological aspects of this new syndrome (Priest and Alexander, 1957;Summerskill, 1959; Gregory,Tracy, French, and Sircus, 1960; Grossman, Tracy, a...
متن کاملZollinger-Ellison Syndrome
Epidemiology The incidence of gastrinomas is 0.5-2/million population/year. [3] 20-30% of patients have ZES as part of MEN1, an autosomal dominant disorder. [4] Mean age of presentation is around 40, being younger in MEN1 patients than sporadic cases. Only about 3% present before age 20 and 7% after age 60. Gastrinomas are the most common functioning tumour of the pancreas. In addition to secre...
متن کامل[Zollinger-Ellison syndrome].
The preoperative localization of gastrinomas often fails despite all modern imaging methods. Therefore, after biochemical confirmation of the diagnosis and exclusion of diffuse metastases, a meticulous surgical exploration including intraoperative ultrasound (IOUS) and duodenal exploration after duodenotomy should be performed. The experienced surgeon will be able to identify more than 90% of t...
متن کامل[Zollinger-Ellison syndrome].
Medical management of patients with Zollinger-Ellison syndrome has considerably evolved since initial reports in 1955 and especially over the last decade. Control of gastric hypersecretion by effective antisecretory drugs, accurate localization and staging of the tumoral process by modern medical imaging techniques as well as progress in surgical skill undoubtedly account for higher rates of ga...
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ژورنال
عنوان ژورنال: The Korean Journal of Thoracic and Cardiovascular Surgery
سال: 2019
ISSN: 2233-601X,2093-6516
DOI: 10.5090/kjtcs.2019.52.6.420